It is currently impossible to reproduce the fur patterns of calico cats by cloning. In other projects Wikimedia Commons. Calico cats may have already provided findings relating to physiological differences between male and female mammals. This page was last edited on 8 October , at
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We've made returning items as easy as possible. In genetic terms, calico cats are tortoiseshells in every way, except that in addition they express a white spotting gene. There is however one anomaly: This reflects the genetic effects on relative speeds of migration of melanocytes and X-inactivation in the embryo.
Serious study of calico cats seems to have begun about when Murray Barr and his graduate student E. Bertram noticed dark, drumstick -shaped masses inside the nuclei of nerve cells of female cats, but not in male cats.
These dark masses became known as Barr bodies. In the absence of other influences, such as color inhibition that causes white fur, the alleles present in those orange loci determine whether the fur is orange or not.
Female cats, like all female placental mammals , normally have two X chromosomes. In contrast, male placental mammals, including chromosomally stable male cats, have one X and one Y chromosome. One exception is that in rare cases faulty cell division may leave an extra X chromosome in one of the gametes that produced the male cat. That extra X then is reproduced in each of his cells, a condition referred to as XXY, or Klinefelter syndrome.
Such a combination of chromosomes could produce tortoiseshell or calico markings in the male, in the same way as XX chromosomes produce them in the female. All but about one in three thousand of the rare calico or tortoiseshell male cats are sterile because of the chromosome abnormality, and breeders reject any exceptions for stud purposes because they generally are of poor physical quality and fertility.
In any event, because the genetic conditions for calico coloring are X linked, a fertile male calico's coloring would not have any determination in the coloring of any male offspring who would receive the Y, not the X chromosome from their father. As Sue Hubble stated in her book Shrinking the Cat: Genetic Engineering before We Knew about Genes ,. The mutation that gives male cats a ginger-colored coat and females ginger, tortoiseshell, or calico coats produced a particularly telling map.
The orange mutant gene is found only on the X, or female, chromosome. As with humans, female cats have paired sex chromosomes, XX, and male cats have XY sex chromosomes. The female cat, therefore, can have the orange mutant gene on one X chromosome and the gene for a black coat on the other. The 'from' price must be lower than the 'to' price.
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